Development of Pacs is new opportunity for changing in the health system. Pacs including emerging technologies that provide accessibility to medical images via the network. Patient health records will be available through detailed video and film in everywhere and any time and with minimal cost. There is no trustee Pacs now in Iran and officials are looking to set up a center for the development Pacs. Under these conditions, identifying factors affecting the adoption of this technology will be very necessary and useful. This study is a correlation –descriptive research that was conducted in 1393. In this research TAM model is used for technology adoption. Variables affecting the technology extracted from the literature and these variables have been prioritized by the Delphi method and expert’s opinion. The model is analyzed by the structural equation method. Data’s was collected by a questionnaire including 16 items of the questionnaire that in this area was mined and were localized for Pacs technology. The target population was 130 of professionals. results of this study at medical centers using of Pacs technology confirmed, the effect of perceived financial costs on behavioral intention of Pacs (t-value = 12/31), the effect of compatibility on perceived usefulness by users (t-value = 8/74), the effect of image on perceived usefulness by users (t-value = 5/69), the effect of the image on the perceived ease of use (t-value = 12/74). According to the findings of this study, the factors affecting the acceptance Pacs were identified from the perspective of users' behavior. The results can be useful in planning of health system for the fair use of health cares and development and equipping of health centers.